Growth Hormone

Growth hormone research examines the hypothalamic-pituitary growth hormone axis and its influence on growth, metabolism, tissue repair and insulin-like growth factor signalling.

Growth hormone secretion is naturally regulated through several interacting signals. Growth hormone-releasing hormone stimulates pituitary GH secretion, while somatostatin acts as an inhibitory signal. Ghrelin receptors and related pathways can also influence pulsatile GH release.

Research peptides including growth hormone secretagogues and growth hormone-releasing hormone analogues allow scientists to investigate different components of this regulatory system. Compounds may differ in receptor selectivity, duration of activity and the pattern of signalling they produce.

Researchers also study downstream pathways involving insulin-like growth factor 1 (IGF-1), which mediates many—but not all—of growth hormone's biological effects. These pathways have relevance to research involving skeletal muscle, connective tissue, metabolism, body composition and cellular growth.

Another important area is the pulsatile nature of normal growth hormone secretion. Frequency and amplitude of GH pulses vary with sleep, exercise, age, nutritional status and other physiological factors, making the GH axis a sophisticated model for endocrine research.

This category brings together compounds associated with growth hormone and related endocrine signalling studies.

All compounds are provided for controlled laboratory research only and are not supplied for hormone replacement, bodybuilding or therapeutic administration.